Distinct Motifs in the Human Serotonin Transporter Carboxyl-terminus Direct Protein Folding and Trafficking
نویسندگان
چکیده
II DECLARATION Herewith I declare that the experiments of the present thesis were carried out under the supervision of Univ. Prof. Dr. Michael Freissmuth. Each article in the " Results " section contains a small introduction with the information which experiments were conducted by me. purified the peptides used for the ATPase assays in section 2.1 fig.1 C, D.
منابع مشابه
A 18 The role of the carboxyl terminus in folding of the serotonin transporter
Background The serotonin transporter (SERT) is a member of the SLC6 family of solute carriers. SERT plays a crucial role in synaptic neurotransmission by retrieving released serotonin. The intracellular carboxyl terminus of various neurotransmitter transporters has been shown to be important for the correct delivery of SLC6 family members to the cell surface. A previous study showed that deleti...
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Background The serotonin transporter (SERT) is a member of the SLC6 family of solute carriers. SERT plays a crucial role in synaptic neurotransmission by retrieving released serotonin. The intracellular carboxyl terminus of various neurotransmitter transporters has been shown to be important for the correct delivery of SLC6 family members to the cell surface. A previous study showed that deleti...
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